Biotechnology

Residues of complex mixtures
Residues of complex organic mixtures are often produced in biotechnological production processes. The cleaning of fermenters and production equipment is therefore a particularly difficult task. Proteins, for example, are especially critical and undesirable because their presence can lead to cross-contamination. And any cleaner residues can also interfere with cell growth.  

Wide application spectrum
In the technical centre at Borer Chemie AG, we develop and optimize aqueous cleaning processes. Tailor-made individual solutions take into consideration both the specific residues and the substrate to be cleaned.  

The proposed processes are ideally suited
> for manual cleaning
> semi-automatic cleaning processes
> automatic processes in washers or
> fully automatic cleaning processes with CIP systems

The focus is on efficient and economical cleaning processes. Also contact us for any further question about cleaning validation.

Production of API

Stubborn residues
A wide variety of organic chemical residues occur during the production of active pharmaceutical ingredients. In many cases, an efficient aqueous cleaning process can be used to remove such residues instead of the costly dissolution of such residues in organic solvents. This is also an important contribution to workplace health and safety.  

Your advantage - our core competence
The specialists at Borer Chemie AG adapt the development and optimization of your cleaning process specifically to the equipment used and the properties of the residues. You benefit from optimum cleaning processes, leading to residue-free surfaces and increased productivity through less downtime.  

Applications
The most important are
> manual cleaning with or without mechanical assistance
> semiautomatic cleaning processes
> automatic processes in washers
> fully automatic cleaning processes with integrated CIP systems

Cleaning validation?
Contact us for further information about cleaning validation! Prove the absence of possible cleaner residues by using our specific and validated analytical methods.

Production of drugs

Typical residues
The removal of active ingredients and in particular of inactive ingredients in the production of solid, semi-solid and liquid drugs is often a major challenge.  

When developing individual cleaning processes, Borer Chemie AG also takes into account the physical-chemical nature of the residues.  

Our know-how - your advantage
Take advantage of our professional know-how and experience. Borer Chemie AG develops optimum and efficient processes for manual cleaning with or without mechanical assistance, semiautomatic cleaning processes, automatic processes in washers, and fully automatic cleaning with integrated CIP systems.Contact us and benefit from our services for cleaning validation.  

Residue-free cleaning
Batch containers, Sieves, Mixers, Tabletting machines, Homogenizers, Filling equipment, Granulators, Small parts from production, Containers, ...  

Ask us for customized cleaning procedures adapted to your specific equipment.

Pharmaceutical Applications and Cleaning Validation

Focusing on cleaning validation - aqueous cleaning meets the most stringent requirements
GMP, cGMP and ICH regulations have resulted in cleaning validation becoming an essential part of the production of drugs and active pharmaceutical ingredients. The cosmetic industry also sets very high standards for cleaning processes. Cleaning validation is nowadays a prerequisite

> for the production of active pharmaceutical ingredients
> in the manufacture of drugs
> in the biotechnology industry

Effective and residue-free cleaning processes at Borer Chemie AG, the cleaning process is at the very centre of things. Effective and residue-free cleaning is achieved through the combination of an individual cleaning process and the appropriate choice of a detergent. Increase productivity through less downtime! Let Borer Chemie AG demonstrate its competence in the development of new processes or the optimization of existing aqueous cleaning processes! Our services and products will enable you to achieve successful cleaning validation.